High density lipoproteins (HDL) are involved in cholesterol uptake from the cells. HDL-cholesterol has a protective effect impeding plaque formation and shows an inverse relationship to coronary heart disease (CHD) prevalence.
A number of factors contribute to low HDL-cholesterol levels: e.g. overweight and obesity, smoking, physical inactivity, drugs such as beta-blockers and progestational agents, genetic factors.
|Adults||National Cholesterol Education Program (NCEP) guidelines:|
|Major risk factor for relationship to coronary heart disease (CHD)||< 40 mg/dL (< 1.04 mmol/L)|
|"Negative" risk factor for CHD||≥ 60 mg/dL (≥ 1.55 mmol/L)|
For information on clinical relevance, please refer to the package insert.