α-Hydroxybutyrate dehydrogenase (α-HBDH)
α-Hydroxybutyrate dehydrogenase (α-HBDH) occurs in higher levels in heart muscle tissue and therefore is more sensitive and specific in diagnosis of myocardial infarction.
|Adults||25° C||37° C|
|< 140 U/L||< 182 U/L|
|< 2.33 µkat/L||< 3.03 µkat/L|
For differentiation between liver and heart diseases the HBDH/LDH ratio can be calculated. A high ratio can be measured in myocardial infarction while a low HBDH/LDH ratio indicates parenchymal liver diseases.
Normal ratio: HBDH/LDH = 0.63 – 0.81
Myocardiac lesion: HBDH/LDH > 0.9
Liver damage: HBDH/LDH < 0.6