Creatinine (Jaffé-method)

Creatinine is an excretion product of the kidney, therefore increased plasma values indicate impaired kidney function.

Reference Ranges

Serum / Plasma, Jaffé-method not compensated
Women0.6 – 1.1 mg/dL53 – 97 µmol/L
Men0.7 – 1.3 mg/dL62– 115 µmol/L
Children
Neonate0.5 – 1.2 mg/dL44 – 106 µmol/L
Infant0.4 – 0.7 mg/dL35 – 62 µmol/L
Child0.5 – 1.2 mg/dL44 – 106 µmol/L
Serum / Plasma, Jaffé-method compensated
Women0.5 – 0.9 mg/dL44 – 80 µmol/L
Men0.7 – 1.2 mg/dL62 – 106 µmol/L
Children
Neonate0.24 – 1.04 mg/dL21 – 92 µmol/L
Infant0.17 – 0.42 mg/dL15 – 37 µmol/L
Child0.24 – 0.87 mg/dL21 – 77 µmol/L
24h Urine
Women11 – 20 mg/kg/d97 – 177 µmol/kg/d
Men14 – 26 mg/kg/d124 – 230 µmol/kg/d
Creatinine clearance
Women95 – 160 mL/min/1.73 m²
Men98 – 156 mL/min/1.73 m²
Albumine/creatinine ratio (early morning urine)
< 30 mg/g Creatinine
Each laboratory should check if the reference ranges are transferable to its own patient population and determine own reference ranges if necessary. For diagnostic purposes, the results should always be assessed with the patient’s medical history, clinical examinations and other findings.

Increased in

  1. Impaired renal function. Serum creatinine is a more specific indicator of renal disease than is serum urea.
  2. Urinary tract obstruction
  3. Diabetes
  4. Rhabdomyolsis
  5. Acromegaly
  6. Nephritis

Decreased in

  1. Decreased muscle mass (e.g. muscular dystrophy, myasthenia gravis)

Conversion

Use our conversion tool to quickly convert between conventional units and SI units

mg/dL
µmol/L

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