Glutamate dehydrogenase (GLDH)

Glutamate dehydrogenase (GLDH) is a mitochondrial enzyme used to evaluate the extent of parenchymal liver damage and, in conjunction with other enzymes in the differential diagnosis of liver disorders.

Reference Ranges

DGKCDeutsche Gesellschaft für Klinische Chemie
Women≤ 5.0 U/L≤0.083 µkat/l
Men≤ 7.0 U/L≤0.117 µkat/l
Each laboratory should check if the reference ranges are transferable to its own patient population and determine own reference ranges if necessary. For diagnostic purposes, the results should always be assessed with the patient’s medical history, clinical examinations and other findings.

Increased in

  1. Necrosis of hepatocytes
  2. Acute toxic liver necrosis
  3. Hypoxic liver diseases

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