Homocysteine

Increased plasma homocysteine is a sensitive marker of folate and vitamin B12 deficiency and an independent risk factor for cardiovascular disease.

Reference Ranges

Women
< 30 years6 – 14 µmol/L
30 – 59 years5 – 13 µmol/L
> 60 years7 – 14 µmol/L
Men
< 30 years6 – 14 µmol/L
30 – 59 years6 – 16 µmol/L
> 60 years6 – 17 µmol/L
> 85 years15 – 30 µmol/L
Each laboratory should check if the reference ranges are transferable to its own patient population and determine own reference ranges if necessary. For diagnostic purposes, the results should always be assessed with the patient’s medical history, clinical examinations and other findings.

Increased in

  1. Folate deficiency
  2. Cobalamin (vitamin B 12) deficiency
  3. Indication CVD risk

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