Immunoglobulin E

Immunglobulin E (IgE) is involved in hypersensivity reactions, therefore elevated levels occur in e.g. atopic diseases, parasitic infection or severe burns.

Reference Ranges

Adults≤ 100 IU/mL
Newborns≤ 1.5 IU/mL
1st year≤ 15 IU/mL
1 – 5 years≤ 60 IU/mL
6 – 9 years≤ 90 IU/mL
10 – 15 years≤ 200 IU/mL
Each laboratory should check if the reference ranges are transferable to its own patient population and determine own reference ranges if necessary. For diagnostic purposes, the results should always be assessed with the patient’s medical history, clinical examinations and other findings.

Increased in

  1. Atopic diseases
  2. Parasitic infection
  3. Diseases with T-cell dysfunction (e.g. AIDS)
  4. Certain malignant tumors (e.g. respiratory tract, gastrointestinal tract)
  5. Hyper-IGE-syndrome
  6. Graft-versus host disease
  7. Severe burns

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