Prealbumin is a negative acute phase protein with decreasing concentration in presence of inflammations. Moreover, it is a liver specific enzyme, allowing assessment of protein malnutrition or liver dysfunction.

Reference Ranges

Serum/Plasma0.2 – 0.4 g/L
Each laboratory should check if the reference ranges are transferable to its own patient population and determine own reference ranges if necessary. For diagnostic purposes, the results should always be assessed with the patient’s medical history, clinical examinations and other findings.

Increased in

  1. Use of glucocorticoids, anabolic steroids and androgens
  2. Acute alcohol intoxication

Decreased in

  1. Protein malnutrition
  2. Inflammation
  3. Postsurgical period
  4. Intake of estrogen


< All Reference Ranges