Alanine Aminotransferase (ALAT / GPT)
Alanine Aminotransferase (ALAT/ALT) is a liver specific enzyme, only significantly elevated in hepatobiliary diseases.
Reference Ranges
| IFCCInternational Federation of Clinical Chemistry and Laboratory Medicine, with pyridoxal-5-phosphate activation | ||
|---|---|---|
| Women | < 34 U/L | < 0.57 µkat/L |
| Men | < 45 U/L | < 0.75 µkat/L |
| Children | ||
|---|---|---|
| 1 - 30 days | < 25 U/L | < 0.42 µkat/L |
| 2 - 12 months | < 35 U/L | < 0.58 µkat/L |
| 1 - 3 years | < 30 U/L | < 0.50 µkat/L |
| 4 - 6 years | < 25 U/L | < 0.42 µkat/L |
| 7 - 9 years | < 25 U/L | < 0.42 µkat/L |
| 10 - 18 years | < 30 U/L | < 0.50 µkat/L |
| Without pyridoxal-5-phosphate activation | ||
|---|---|---|
| Women | < 31 U/L | < 0.52 µkat/L |
| Men | < 41 U/L | < 0.68 µkat/L |
Each laboratory should check if the reference ranges are transferable to its own patient population and determine own reference ranges if necessary. For diagnostic purposes, the results should always be assessed with the patient’s medical history, clinical examinations and other findings.
For information on clinical relevance, please refer to the package insert.