2021-12-02: Quantitative anti-SARS-CoV-2 total antibody determination in WHO standardized units (BAU/mL)
DiaSys is particularly pleased to announce the standardization of the SARS-CoV-2 UTAB FS (UTAB = Universal Total AntiBody) assay.
The quantitative SARS-CoV-2 UTAB FS assay had been developed before an international standard for anti-SARS-CoV-2 immunoglobulins was available. Therefore, the manufacturer specific unit AU/mL had to be initially assigned. Since the first WHO International Standard for anti-SARS-CoV-2 immunoglobulin (human) NIBSC code 20/136* is now available, DiaSys has correlated the calibrator of the test SARS-CoV-2-UTAB FS in a linear regression comparison.
The WHO International Standard correlates well with the current standardization of the DiaSys SARS-CoV-2 UTAB FS assay. Since the manufacturer-specific unit AU/mL is essentially equivalent to the BAU/mL unit of the first WHO international standard for anti-SARS-CoV-2 immunoglobulin (human) NIBSC code 20/136, results will be reported in BAU/mL in the future.
Due to the standardization and the resulting adaptation of the calibrators, the measuring range could be extended to 250 BAU/mL. More information about the quantitative anti-SARS-CoV-2 total antibody assay in WHO standardized units can be found here.