Immunoglobulin M

Immunglobulin M (IgM) binds to antigens and triggers antigen catabolism. Decreased concentrations are caused by immunodeficiency syndromes, elevated IgM levels are observed in severe infections and autoimmune diseases.

Reference Ranges

Adults40 – 230 mg/dL0.41 – 2.37 µmol/L
Children
Newborns10 – 30 mg/dL0.10 – 0.31 µmol/L
1 – 3 months10 – 70 mg/dL0.10 – 0.72 µmol/L
4 – 6 months20 – 100 mg/dL0.21 – 1.03 µmol/L
7 – 12 months30 – 100 mg/dL0.31 - 1.03 µmol/L
2 years40 – 140 mg/dL0.41 – 1.44 µmol/L
3 – 5 years40 – 180 mg/dL0.41 – 1.85 µmol/L
6 – 9 years40 – 160 mg/dL0.41 – 1.65 µmol/L
10 – 13 years40 – 150 mg/dL0.41 – 1.55 µmol/L
Each laboratory should check if the reference ranges are transferable to its own patient population and determine own reference ranges if necessary. For diagnostic purposes, the results should always be assessed with the patient’s medical history, clinical examinations and other findings.

Increased in

  1. Infections
  2. Hyper-IgM dysgammaglobulinemia
  3. Waldenström´s Macroglobulinemia
  4. Autoimmune disease

Decreased in

  1. Immunodeficiency diseases
  2. Non-IgM Myeloma
  3. Protein-losing syndromes infancy, early childhood

Conversion

Use our conversion tool to quickly convert between conventional units and SI units

mg/dL
µmol/L

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