Total bile acids


Total bile acids serve as a marker for liver function. Increased serum TBA levels can indicate acute and chronic hepatitis, intrahepatic cholestasis of pregnancy (ICP), liver sclerosis, cirrhosis, and cancer. 

Determination of total bile acids in human stool plays an increasingly important role for the diagnosis of bile acid diarrhea (BAD), irritable bowel syndrome with diarrhea (IBS-D) or Crohn’s disease.

Reference Ranges

TBA for application in human serum samples
< 10 µmol/L (fasting)
TBA for application in human stool samples
Female4.5 – 70.3 μmol/L
Male4.3 – 83.8 μmol/L
Each laboratory should check if the reference ranges are transferable to its own patient population and determine own reference ranges if necessary. For diagnostic purposes, the results should always be assessed with the patient’s medical history, clinical examinations and other findings.

For information on clinical relevance, please refer to the package insert.


< All Reference Ranges